The Modell Lab at Johns Hopkins School of Medicine is seeking a Research Technologist to study CRISPR-Cas9 biology. The Modell Lab studies how CRISPR-Cas9 systems function in nature to provide their bacterial hosts with adaptive immunity against phages and plasmids. We ask fundamental biological questions with an array of approaches including genetics, genomics, molecular biology, biochemistry, bioinformatics and microbiology. Our studies provide insights into (i) bacterial decision-making and stress responses, (ii) the emerging field of phage therapy for antibiotic resistant bacterial infections and (iii) the development of new and improved Cas9 tools.
* The hiring team is requesting that each candidate provide a cover letter. In your cover letter, please describe your (i) previous research experience, and (ii) you research interests and future career goals
Specific Duties & Responsibilities:
Follows established protocols and uses aseptic technique to perform laboratory tests and experiments which may include: propagating and manipulating bacterial cell cultures and bacteriophages, cloning and sequencing plasmid constructs, performing molecular biology techniques such as PCR, DNA gel electrophoresis and nucleic acids purification, preparation of DNA libraries for deep sequencing, Western and Northern blots, and/or human cell culture and Cas9 editing experiments.
Keeps a detailed electronic laboratory notebook.
Participates in journal clubs and develops skills in written and oral communication.
Manages and organizes laboratory equipment, protocols, databases and inventory.
Prepares specialized buffers and reagents to support all lab members.
Complies with biohazard/radiation safety standards through proper handling of potentially hazardous chemical and biological agents and/or radiation sources in the workplace.
Actively seeks to increase skills and expertise.
Performs miscellaneous related duties as assigned. For an example of our work, please see our recent paper or check out our website.
Minimum Qualifications (Mandatory):
Bachelor's Degree in Biology, Chemistry or related field.
* Applicants who do not meet the posted requirements but are completing their final academic semester/quarter will be considered eligible for employment and may be asked to provide additional information confirming their academic completion date.
1 year of laboratory experience.
Independent research project not related to normal course requirements preferred.
Classified Title: Research Technologist Role/Level/Range: ACRO40/E/02/CC Starting Salary Range: $15.00 - $20.00/hr (commensurate with experience) Employee group: Full Time Schedule: M-F, 8:30am - 5pm Exempt Status: Non-Exempt Location: School of Medicine Campus Department name: SOM MBG Molecular Biology and Genetics Personnel area: Johns Hopkins University
The successful candidate(s) for this position will be subject to a pre-employment background check.
If you are interested in applying for employment with The Johns Hopkins University and require special assistance or accommodation during any part of the pre-employment process, please contact the Talent Acquisition Office at [email protected]. For TTY users, call via Maryland Relay or dial 711.
The following additional provisions may apply, depending on campus. Your recruiter will advise accordingly.
The pre-employment physical for positions in clinical areas, laboratories, working with research subjects, or involving community contact requires documentation of immune status against Rubella (German measles), Rubeola (Measles), Mumps, Varicella (chickenpox), Hepatitis B and documentation of having received the Tdap (Tetanus, diphtheria, pertussis) vaccination. This may include documentation of having two (2) MMR vaccines; two (2) Varicella vaccines; or antibody status to these diseases from laboratory testing. Blood tests for immunities to these diseases are ordinarily included in the pre-employment physical exam except for those employees who provide results of blood tests or immunization documentation from their own health care providers. Any vaccinations required for these diseases will be given at no cost in our Occupational Health office.
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