The Department of Ophthalmology is seeking a Research Specialist who will work in a multi-disciplinary lab and will carry out research into the pathological mechanisms of glaucoma in a team environment.
Specific Duties & Responsibilities:
Perform various glaucoma model and optic nerve ophthalmic surgeries and intraocular injections in mice and rats, preparing and dosing animals in drug studies, measuring intraocular pressure using rebound tonometry, using injectable or gas anesthetics via commercial rodent anesthesia machine in accordance with USDA and AALAC.
Prepare and carry out perfusion fixation and micro-dissection of ocular tissues.
Histological methods performed in this position include cryopreservation and epoxy preparation (embedding and sectioning) for immunofluorescent and/or morphologic studies of animal and human donor eye tissues.
Management of multiple mouse lines, performing ear punches, breeding and tail PCF to genotype, maintaining database of mouse lines.
Image capture and data analysis for morphological studies using analysis programs such as Metamorph, Imaris, and ImageJ.
Confocal and or 2 photon imaging of immuno-labelled tissues.
Execute proper disposal of biohazardous materials, maintain laboratory conditions and other duties as assigned by Lab Manager.
Minimum Qualifications (Mandatory):
BS or BA in Biology or related science with 1-3 years' experience, or Master's Degree in related field.
1 year experience in a Cell Biology, Molecular Biology or Neuroscience laboratory performing relevant techniques is desired.
Special Knowledge, Skills & Abilities:
Histology, animal surgery and microdissection, immunofluorescence microscopy, and confocal microscopy desired.
This position requires working with rodents on a frequent basis. Those candidates with pre-existing allergies to rodents or cats and/or have asthma will be unsuitable for this job.
Classified Title: Research Specialist Role/Level/Range: ACRP/03/MA Starting Salary Range: $16.18 - $22.16/hr (commensurate with experience) Employee group: Full Time Schedule: Mon-Fri 8:30-5 Exempt Status: Non-Exempt Location: School of Medicine Campus Department name: SOM Oph Glaucoma Personnel area: School of Medicine
The successful candidate(s) for this position will be subject to a pre-employment background check.
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