The Research Assistant is a part of the Department of Biochemistry in the School of Medicine at Vanderbilt University and is a key laboratory member responsible for duties necessary for maintaining efficient laboratory function, such as preparing stocks, organizing lab supplies, and assisting with various research projects. This position requires a motivated individual who will contribute to collaborations with other researchers within the lab, while also working independently to efficiently complete assigned tasks. Reporting directly to the Principal Investigator, the Research Assistant will collaborate closely with members of the laboratory as well as other members of the Vanderbilt Department of Biochemistry and Center for Structural Biology.
The Brown Laboratory focuses on understanding defects in macromolecular protein assembly that underlie human disease. Specifically, using X-ray crystallography and related techniques, we seek to solve the 3-D structures of the individual protein components of large assemblies known to be critical for proper mitochondrial physiology; defects in which cause severe diseases ranging from anemia to neurodegeneration. Ultimately, we can use this detailed molecular information to uncover how genetic mutations cause changes in protein folding, leading to aberrant assembly and subsequent human disease. In addition to X-ray crystallography, the laboratory also employs a wide range of biochemical and biophysical techniques to complement our structural work, including mass spectrometry, fluorescence-based enzyme assays, analytical ultracentrifugation, and various binding assays, to name few. Members of the laboratory will be based in the recently-renovated space and will work in a collaborative and interactive community space shared by other biochemistry laboratories.
Duties and Responsibilities
The Research Assistant will be responsible, after appropriate training, for carrying out biochemistry laboratory tasks, including:
Specific duties related to protein biochemi stry experimen ts
Making common laboratory stocks, media, buffers, etc.
Carrying out tasks related to protein expression (e.g. PCR, plasmid preparation, bacterial cell culture growth)
General laboratory tasks
Maintaining laboratory equipment
Cleaning and autoclaving glassware and equipment
Assisting with monitoring and ordering supplies and receiving packages
Other tasks related to science communication
Attendance at regular meetings with Principal Investigator to discuss laboratory tasks and data
Attendance and participation in regular group laboratory meetings
Proficiency and accuracy in maintaining lab notebook and documentation
Assisting Principal Investigator in training other researchers in lab procedures and protocols
A Bachelor's degree in biochemistry, biology, chemistry, or a related field from an accredited institution of higher education is necessary.
Evidence of excellence in laboratory coursework is preferred.
Experience in an academic biochemistry laboratory is strongly preferred.
Experience in a college or university academic laboratory (e.g. post-baccalaureate program or summer internship) is preferred.
Experience in PCR/cloning is preferred.
Experience in protein expression and purification is preferred.
Ability to adhere to environmental health and safety standards is necessary.
Ability to adhere to scientific integrity standards in data collection and reporting is necessary.
Ability to understand and follow scientific research protocols and procedures is strongly preferred.
Proficiency in written and oral scientific communication is preferred.
Ability to work in a collaborative environment and take direction is strongly preferred.
Ability to analyze and interpret scientific data is preferred.
Commitment to Equity, Diversity, and Inclusion
At Vanderbilt University, we are intentional about and assume accountability for fostering advancement and respect for equity, diversity, and inclusion for all students, faculty, and staff. Our commitment to diversity makes us who we are. We have created a community that celebrates differences and lets individuality thrive. As part of this commitment, we actively value diversity in our workplace and learning environments as we seek to take advantage of the rich backgrounds and abilities of everyone. The diverse voices of Vanderbilt represent an invaluable resource for the University in its efforts to fulfill its mission and strive to be an example of excellence in higher education.
Vanderbilt University is an equal opportunity, affirmative action employer. Women, minorities, people with disabilities and protected veterans are encouraged to apply.
Please note, all candidates selected for an offer of employment are subject to pre-employment background checks, which may include but are not limited to, based on the role for which they have been selected: criminal history, education verification, social media review, motor vehicle records, credit history, and professional license verification.
Internal Number: 10000740
About Vanderbilt University
Vanderbilt University is a center for scholarly research, informed and creative teaching, and service to the community and society at large. Vanderbilt will uphold the highest standards and be a leader in the quest for new knowledge through scholarship, the dissemination of knowledge through teaching and outreach, and the creative experimentation of ideas and concepts. In pursuit of these goals, Vanderbilt values most highly intellectual freedom that supports open inquiry, equality, compassion, and excellence in all endeavors.