The Department of Pathology seeks a Sr. Laboratory Coordinator to work with limited supervision, coordinates the operations of the laboratory and is responsible for administrative and scientific activity. Manages tissues of patients on clinical trials including biopsies of prostate cancer patients before and after treatments for sponsored grants and clinical trials. Obtains specimens and performs appropriate examination including frozen sectioning and reported gross. Helps maintain the Tissue Bank and is responsible for proper upkeep of the tissue bank database. Frequent interaction with other teams and disciplines. Handles assigned specimens including annotation, processing, database management and distribution of specimens including to outside investigators. Work also includes slide scanning and managing the image data and laser capture microdissection.
Duties and Responsibilities:
Coordinates operations of the laboratory with responsibility for administrative and scientific activities
Responsible for tissue microarray production for a number of prostate cancer related projects. Will request slides and blocks from Pathology Archives.
Responsible for organization of tissue blocks and slides as well as recording items sent and received in database and documentation of material usage.
Responsible for the maintenance of tissue bank including the database and frozen inventory. This includes the downloading of specimens and data entry of specimens from Open Specimen and TMAJ. Organizes frozen tissue inventory (-80 freezers).
Preparation of tissue samples including but not limited to: Cryostat and microtome sectioning of frozen and paraffin embedded tissue, DNA and RNA extracting from prostate tissue, scoring of stained tissue, quantifying staining intensity, preparing and reporting on slides. Utilizes expertise in determining process and handling of specimens.
Complete efficient collection and distribution of prostate tissue samples and extracts. Responsible for acquisition, storage, database entry, and characterization of Prostate specimens. Recording all data and the distribution of` samples according to written protocols and quality assurance procedures. Provide general gross room support such as retrieving case from the OR, preparing specimens for tissue harvesting, specimen photography.
Utilizes discretion in budget support and ordering of supplies/inventory. Tracks and insures adherence to grant related expenses.
Bachelor’s degree in biology, chemistry, or related major. Three years of related experience. Master's degree, with related graduate research, may substitute for experience to the extent permitted by the JHU equivalency formula.
JHU Equivalency Formula: 30 undergraduate degree credits (semester hours) or 18 graduate degree credits may substitute for one year of experience. For jobs where equivalency is permitted, up to two years of non-related college course work may be applied towards the total minimum education/experience required for the respective job.
Experience with computers, including, database management and maintenance. Experience with histopathology techniques (microtomy, frozen sections, routine staining, etc.)
Equipment, Machine, or Tool Requirements:
Computer and Laboratory equipment including Cryostat, Microscope, Microtome.
Work Environment /While performing the duties of this job:
While performing the duties of this job, the employee may remain in a stationary position (sitting) up to 30% of the time and standing/walking at 70%.
The employee is required to use hands/fingers to touch, type and/or feel. Will operate computer keyboard, and/or laboratory instruments, small laboratory tools such as pipettes, cutting instruments, glass tubes, dishes, and/or slides.
Prolonged vision requirements including viewing computer screen, paper reports/documents charts and results. Visual acuity is required to distinguish fine gradation of color or structure and closely examine specimens (including via a microscope) for laboratory positions.
Pathology Department Position is primarily in a laboratory environment where:
Exposure to toxins and infectious agents exist, but potential for personal injury or harm is minimized if established safety and health precautions are followed for assigned work areas.
Must refer to and are expected to comply with procedure manuals, follow proper laboratory protocols and safety policy/procedures, and be familiar with material data safety sheets in assigned work areas.
Able to read and understand all Health, Safety and Environment (HSE) guidelines applicable to assigned work area.
Working in laboratory where there may be discomforts due to odors, noise, temperature fluctuations, and working around lab equipment.
Research areas may include animal, human, human products, DNA, and radiation protocols.
Clinical Research and patient care duties may require direct interaction with patients at all levels of health or illness; including those noted with precautions/contagious symptoms or disease.
Use of personal protective equipment may be advised or required.
May transport equipment and supplies usually less than 40 pounds from one area to another including laboratory supplies or luggage. May be required to lift and/or move up to 50 pounds with proper training, or precautions/lifting aides. In some areas work space is limited.
While most of our positions require on-site presence; where positions are approved for alternate work locations (remote work) – specific expectations will be outlined and documented; and the safety of work environment, security of work information, and productivity measures are regularly reviewed with employees and subject to on-going approval by management. Staff should be aware of and report other remote work implications and requirements that may impact them or the organization.
Staff may be required to complete annual competency review, and must insure compliance with Johns Hopkins Policy, Laboratory Policy & Procedure, Health, Safety & Environment regulations, and all applicable privacy & confidentiality laws/practices. Annual training and testing requirements.
Some areas maintain 24/7 operations and may require rotating shifts, evening, overnight, weekend, or holiday schedules. Some areas require on-call duties.
Where designated positions are clinical or required attendance. In the event of a declared emergency; including but not limited to weather events, major disasters, or community unrest/events – staff may be required to report to work and/or remain at work.
Classified Title:Sr. Laboratory Coordinator Role/Level/Range: ACRP/03/MB Starting Salary Range: $38,920.00 - $53,520.00; Commensurate with experience Employee Group: Full Time Schedule: Monday - Friday, 8:30am - 5:00pm/May require rotating shifts, evening, overnight, weekend, or holidays Exempt Status: Exempt Location: School of Medicine, East Baltimore Campus Department Name: Pathology Kidney Urologic Pathology Personnel Area: School of Medicine
The successful candidate(s) for this position will be subject to a pre-employment background check.
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The following additional provisions may apply depending on which campus you will work. Your recruiter will advise accordingly.
During the Influenza ("the flu") season, as a condition of employment, The Johns Hopkins Institutions require all employees who provide ongoing services to patients or work in patient care or clinical care areas to have an annual influenza vaccination or possess an approved medical or religious exception. Failure to meet this requirement may result in termination of employment.
The pre-employment physical for positions in clinical areas, laboratories, working with research subjects, or involving community contact requires documentation of immune status against Rubella (German measles), Rubeola (Measles), Mumps, Varicella (chickenpox), Hepatitis B and documentation of having received the Tdap (Tetanus, diphtheria, pertussis) vaccination. This may include documentation of having two (2) MMR vaccines; two (2) Varicella vaccines; or antibody status to these diseases from laboratory testing. Blood tests for immunities to these diseases are ordinarily included in the pre-employment physical exam except for those employees who provide results of blood tests or immunization documentation from their own health care providers. Any vaccinations required for these diseases will be given at no cost in our Occupational Health office.
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