The Dawson laboratory studies the cell death pathways of neurodegenerative diseases. For this advertisement, the current study focuses on the motor and non-motor symptoms of Parkinson’s disease and neural injury in stroke, using mouse models and cell culture assays. We employ a myriad of techniques including protein analysis via western blot and translation assays, live-cell fluorescent imaging, immunohistochemistry/immunocytochemistry, stereotaxic injections, surgery, viral circuit tracing, and new projects utilizing optogenetics, DREADS, in vivo electrophysiology and calcium imaging paired to behavior assays. The Dawson laboratory is diverse with over 40 people that include instructors, postdocs, technicians, and graduate and undergraduate students from all over the world.
Under the general supervision of a junior investigator, the technologist will be responsible for animal husbandry of a transgenic mouse colony.
Will maintain breeding colony of multiple mouse strains, including record keeping and genotyping.
Injecting animals and harvesting primary tissue specimens according to protocols.
Will perform and analyze behavioral tasks.
Maintains and makes minor adjustments to equipment.
Aids manager with laboratory support related tasks and biosafety adherence.
Will harvest and process brains for immunohistochemistry/immunocytochemistry, and imaging.
With more experience the technician will also be expected to assist with other investigator’s studies within the Dawson laboratory.
All training needed to perform the required tasks will be provided.
Bachelor’s degree in biology, chemistry or related field required.
Some related post-undergraduate lab experience with general molecular biology techniques such as PCR and gel electrophoresis are desired as is mouse handling.
Classified title: Research Technologist
Working title: Research Technologist
Role/Level/Range: ACRO 40/E/02/CC
Starting Salary Range: $14.14 - $19.44 (commensurate with experience)
Employee group: Full-Time
Employee Status: Non-Exempt
Schedule: Monday-Friday –8:30am-5:00pm 40hrs/Wk
Location: MRB 714 - 733 N. Broadway, Baltimore, MD
Department name: 10002871-SOM ICE Neuroregeneration - Institute for Cell Engineering
Personnel area (School): SOM – School of Medicine
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