The Center for Functional Cancer Epigenetics (CFCE) is dedicated to the exploration of the key role that epigenetic alterations and abnormal transcriptional regulation play in the development and progression of cancer. A better understanding of these alterations will lead to better diagnosis for cancer and contributions to the knowledge required for the development of new therapeutics exploiting epigenetic mechanisms. The Center's organization and leadership represents a very tight coupling between wet-lab and informatics efforts that provides an unprecedented opportunity to advance the field.
The Sr. Research Technician will perform experiments under the supervision ofthe Associate Director and a Lead scientist. They will be focused on projects that elucidate epigenetic and transcriptional regulation in wide variety of cancer models as well as patient samples. This will involve a variety of genomic techniques including RNA and DNA extraction, nuclear isolation, ChIP-seq and ATAC-seq (bulk and single cell). The candidate will support current team goals and practices by producing high-quality data, being actively involved in troubleshooting experiments, maintaining a comprehensive lab notebook and managing computer data files.
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
Set up, adjust, calibrate, clean, maintain and troubleshoot equipment.
Clean, maintain and prepare supplies and work areas and may be responsible for ordering of supplies. Collaborates with Purchasing and may be responsible for negotiating with vendors.
Conduct standardized biological, microbiological or biochemical tests and laboratory analyses, including the collection of information and samples from organic substances, such as blood, drugs, and animals.
Isolate, identify and prepare specimens for examination.
Analyze experimental data and interpret results to write reports and summaries of findings, including grant preparation and presentations, and look for opportunities to co-author publications. May be expected to participate in formal and information presentations of results to staff.
Participate in grant application process and manuscript preparation as required.
Maintains detailed notebook of all work-related activities.
Monitors laboratory work to ensure compliance with Environmental Health and Safety information as well as the standard operation procedures specific to each laboratory.
Expected to provide intellectual and interactive commitment to position by keeping up with appropriate literature and research publications.
May be responsible for the development, modification and improvement of standard operating procedures.
Uses computers, computer-interfaced equipment, robotics or high-technology applications to perform work duties.
May be responsible for designing and executing advanced experiments and setting strategy.
May be responsible for the examination of animals and specimens to detect the presence of disease or other problems.
May be responsible for monitoring laboratory budgets.
The ideal candidate will be collaborative, self-directed and possess the following:
-A Bachelor's degree (or higher) in biology or a related field
-Familiarity with basic laboratory techniques and principles of molecular biology
-Excellent time management, organizational and communication skills
-At least one year of lab experience with genomic technologies preferred, or equivalent combination of education and experience
-Must effectively solve problems with minimal supervision
-Should enjoy working both independently and as part of a team
-Additional activities may include presenting reviewing data, presenting results to collaborators and assisting with preparing manuscripts
-Solid understanding of cancer biology a plus
Ability to work within a team environment.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.
Internal Number: 2021-20855
About Dana-Farber Cancer Institute
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to under-served members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.