The Research Specialist II will work on funded projects related to the study of the mechanisms and target identification for Huntington’s Disease and will provide lab support for ongoing clinical studies for HD.
Under the supervision of a faculty investigator, the research specialist works independently to carry-out research experiments, involving a range of sophisticated assays using modern molecular biology, protein biochemistry and cell biology techniques. Makes significant/important contributions to various aspects of research efforts. Executes independent decision making and trouble-shooting during experiments and participates in designing new methodologies. Utilizes specialized knowledge to interpret results and participates in planning new experimental approaches towards research goals. Uses scientific knowledge and lab experience to make judgments and decisions. Makes scientific contribution to protocol development, efficiency, and productivity. Collaborates in development of new techniques and instruments. Applies published research methods to current experimental work by investigating published protocols and discussing them with PI. Contributes scientifically to writing of manuscripts and grants. Processes analyzed data into figures for scientific publications.
Laboratory management includes tracking supply inventories, placing orders, reimbursements, interface with vendors, laboratory organization, upkeep, and compliance with safety regulations. Equipment maintenance, upkeep, and organization of usage. Works with instrument field applications specialists and engineers to ensure equipment functions properly. Giving recommendations towards purchasing of new equipment and reagents. Teaches/trains students and new technicians in the lab. Guides, directs and facilitates problem solving for entry level lab members on day-to-day basis.
Laboratory management also includes organization of use of equipment by investigators, organization of freezer space, hoods and incubators; maintenance of an efficient laboratory configuration for investigators and proactive attention to the needs of investigators for laboratory resources.
Specific Duties & Responsibilities
Responsible for assigned on-going research projects.
Perform data generation using techniques such as PCR, molecular cloning, gel electrophoresis, biochemical protein purification, tissue preparation and analysis, cell culture and transfection.
Provides lab support for clinical research studies which involved processing of human blood and CSF samples and following specific research/clinical protocols
Use of highly sophisticated techniques, equipment and reagents to perform experiments.
Quality control of the different protocols performed to ensure high standards of experimentation.
Use analytical and programming software, e.g. DNA analysis and proteomics software, to interpret results, make conclusions, and perform quality control tests.
Utilize specialized knowledge to interpret and evaluate results, present results at the lab meetings and participates in the preparation of manuscripts and grants.
Use scientific knowledge and lab experience to make judgments and decisions.
Apply original thought to make decisions with the PI
Make intellectual contributions to scientific research.
Develop, design, and manage substantial research projects and coordinate own objectives.
Order equipment and supplies, interface with vendors, maintains equipment
Assist with trouble-shooting and problem solving.
Performs clinical laboratory procedures for human clinical research studies according to Good Clinical Practice and Good Laboratory Practice, with rigorous adherence to protocols and documentation, and flexible accommodation and re-prioritization of basic lab work duties due to changing clinical schedules and priorities.
Bachelor’s degree in biology, chemistry, or related field required plus at least two years of laboratory experience performing relevant techniques.
* JHU Equivalency Formula: 30 undergraduate degree credits (semester hours) or 18 graduate degree credits may substitute for one year of experience. Additional related experience may substitute for the required education on the same basis. For jobs where equivalency is permitted, up to two years of non-related college course work may be applied towards the total minimum education/experience required for the respective job.
Master's degree, with related graduate research, may substitute for experience to the extent permitted by the JHU equivalency formula. Experience with molecular cloning techniques, PCR, protein gel-electrophoresis and cell culture is preferred.
Must be detail oriented, keep clear experimental records, have effective organizational skills, and be able to prioritize workload appropriately.
Specific physical requirements for the job:
Sufficient eye-hand coordination for performing experiments using hand-held pipettes.
Classified Title: Research Specialist II Working Title: Research Specialist II Role/Level/Range: ACRP/03/MB Starting Salary Range: $38,920 - $53,500; Commensurate with experience Employee group: Full Time Schedule: Monday - Friday, 8:30am to 5:00pm; Up to 37.5 hours per week Exempt Status: Exempt Location: 04-MD:School of Medicine Campus Department name: 10003302-SOM Psy Neurobiology Personnel area: School of Medicine
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