Cerebral malaria (CM) is a serious complication of malaria infection that primarily affects young children in sub-Saharan Africa. Clinical symptoms of CM include coma and seizures. Upon anti-parasitic chemotherapy, a subset of survivors are left with neuro-cognitive deficits. The malaria parasite, Plasmodium falciparum, infects red blood cell (PRBC), which clog up blood vessels and adhere to the brain microvascular endothelial cells of the blood-brain barrier. How these parasites, which reside inside the PRBC’s and inside the vascular lumen mediate neuronal damage is not clear. Our laboratory seeks an individual to conduct research in this field.
Specific Duties & Responsibilities
Carries out standard lab projects and participates in developing assays and protocols for PI approval. Designs experimental approaches for research projects. Perform a range of sophisticated assays. Aid in training students and junior personnel in lab. Requires a good understanding of the work of the lab. Will aid in preparation of manuscripts
Responsible for daily research projects. Performs a range of assays and experiments specific to area of research, including cell culture, RT-PCR, gel electrophoresis, western blotting and fluorescence microscopy. Makes significant/important scientific contributions to various aspects of research efforts and includes routine troubleshooting, independent decisions and training/guidance of other lab personnel. Plans and run set of experiments after discussion with investigator. Work may include making protocol modifications within the parameters set by investigator. Processes and analyzes data into figures for scientific publications. May scientifically contribute to writing of manuscripts and grants.
Orders equipment and supplies and interfaces with vendors
Bachelor's degree in biology, chemistry or related field.
2 years laboratory experience performing relevant techniques.
Master's degree, with related graduate research, may substitute for experience to the extent permitted by the JHU Equivalency Formula: 30 undergraduate degree credits (semester hours) or 18 graduate degree credits may substitute for one year of experience. Additional related experience may substitute for the required education on the same basis. For jobs where equivalency is permitted, up to two years of non-related college course work may be applied towards the total minimum education/experience required for the respective job. *
Master’s degree in science with relevant laboratory experience. Experience with neuroscience is a plus.
Special Knowledge, Skills, and Abilities:
Mammalian tissue culture, standard laboratory techniques, e.g. gel electrophoresis, western blotting, RT-PCR, microscope / fluorescent microscope, etc. Ability to work with standard computer programs, e.g. word, excel, statistics software and willing to learn specialized instrument related computer programs, e.g. ECIS, multiplexing.
Classified Title: Research Specialist II Working Title: Research Specialist II Role/Level/Range: ACRP/03/MB Starting Salary Range: $38,537 - $52,989 / commensurate with experience Employee group: Full Time Schedule: M-F 7.5hrs/day Exempt Status: Exempt Location: 05-MD:School of Public Health Department name: 10001154-W Harry Feinstone Dpt Molec Mblgy Imlgy Personnel area: School of Public Health
The successful candidate(s) for this position will be subject to a pre-employment background check.
If you are interested in applying for employment with The Johns Hopkins University and require special assistance or accommodation during any part of the pre-employment process, please contact the HR Business Services Office at firstname.lastname@example.org. For TTY users, call via Maryland Relay or dial 711.
The following additional provisions may apply depending on which campus you will work. Your recruiter will advise accordingly.
During the Influenza ("the flu") season, as a condition of employment, The Johns Hopkins Institutions require all employees who provide ongoing services to patients or work in patient care or clinical care areas to have an annual influenza vaccination or possess an approved medical or religious exception. Failure to meet this requirement may result in termination of employment.
The pre-employment physical for positions in clinical areas, laboratories, working with research subjects, or involving community contact requires documentation of immune status against Rubella (German measles), Rubeola (Measles), Mumps, Varicella (chickenpox), Hepatitis B and documentation of having received the Tdap (Tetanus, diphtheria, pertussis) vaccination. This may include documentation of having two (2) MMR vaccines; two (2) Varicella vaccines; or antibody status to these diseases from laboratory testing. Blood tests for immunities to these diseases are ordinarily included in the pre-employment physical exam except for those employees who provide results of blood tests or immunization documentation from their own health care providers. Any vaccinations required for these diseases will be given at no cost in our Occupational Health office.
Equal Opportunity Employer Note: Job Postings are updated daily and remain online until filled.
Johns Hopkins University remains committed to its founding principle, that education for all students should be grounded in exploration and discovery. Hopkins students are challenged not just to learn but also to advance learning itself. Critical thinking, problem solving, creativity, and entrepreneurship are all encouraged and nourished in this unique educational environment. After more than 130 years, Johns Hopkins remains a world leader in both teaching and research. Faculty members and their research colleagues at the university's Applied Physics Laboratory have each year since 1979 won Johns Hopkins more federal research and development funding than any other university. The university has nine academic divisions and campuses throughout the Baltimore-Washington area. The Krieger School of Arts and Sciences, the Whiting School of Engineering, the School of Education and the Carey Business School are based at the Homewood campus in northern Baltimore. The schools of Medicine, Public Health, and Nursing share a campus in east Baltimore with The Johns Hopkins Hospital. The Peabody Institute, a leading professional school of music, is located on Mount Vernon Place in downtown Bal...timore. The Paul H. Nitze School of Advanced International Studies is located in Washington's Dupont Circle area.