This position will provide support for a laboratory in the Neuroimmunology and Neurological Infections Division of Department of Neurology at the Johns Hopkins University School of Medicine East Baltimore Campus.
The position is in a disease-oriented research group that addresses questions in basic neurobiology, and in clinical neurology. The primary interests of the group are: 1) To identify biomarkers markers for neurodegenerative diseases including HIV-Associated Neurocognitive Disorder, Alzheimer's disease, Multiple Sclerosis, and traumatic brain injury. 2) To better understand the lipid components of cellular membranes, and how these components interact with proteins to regulate signaling associated with cellular functions such as differentiation, motility, inflammatory signaling and survival. 3) To develop small molecule therapeutics that regulate lipid metabolism as a neuroprotective strategy. The person will be responsible for laboratory management, and for analysis of lipids and metabolites in human and non-human samples obtained from multiple ongoing studies.
Specific duties & responsibilities:
This is primarily a research position. Expertise in multiple laboratory skills is a requirement. Laboratory skills should include RTPCR, viral-vector design (and more importantly utilization of viral-vectors to knock-down selected targets in vivo & tissue culture), fluorescent imaging of cells & tissues, Western blotting, and primary cell culture are required. Knowledge of analysis methods for handling RNAseq, and proteomic data would be an asset.
Exercises managerial or professional judgment and assumes complete responsibility for decisions, consequences, and results. Engages in regular and continuous decision making having an impact on people, costs, and/or quality of service.
Minimum qualifications (mandatory):
BS/BA chemistry, biochemistry or neuroscience. A minimum of two years of related laboratory experience performing relevant techniques.
Previous laboratory experience is required. RTPCR, viral-vector design and utilization, fluorescent imaging of cells & tissues, Western blotting, and primary cell culture. Strong computing skills for various software applications, such as spreadsheets, databases, statistical packages, and graphics packages to assemble, analyze and/or format data and/or test reports.
Classified Title: Research Specialist II Working Title: Research Specialist II Role/Level/Range: ACRP/03/MB Starting Salary Range: $38,920-$53,520 Employee group: Full Time Schedule: M-F, 8:30 am- 5:00 pm Exempt Status: Exempt Location: 04-MD:School of Medicine Campus Department name: 10003522-SOM Neuro Neuroimmunology Personnel area: School of Medicine
The successful candidate(s) for this position will be subject to a pre-employment background check.
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During the Influenza ("the flu") season, as a condition of employment, The Johns Hopkins Institutions require all employees who provide ongoing services to patients or work in patient care or clinical care areas to have an annual influenza vaccination or possess an approved medical or religious exception. Failure to meet this requirement may result in termination of employment.
The pre-employment physical for positions in clinical areas, laboratories, working with research subjects, or involving community contact requires documentation of immune status against Rubella (German measles), Rubeola (Measles), Mumps, Varicella (chickenpox), Hepatitis B and documentation of having received the Tdap (Tetanus, diphtheria, pertussis) vaccination. This may include documentation of having two (2) MMR vaccines; two (2) Varicella vaccines; or antibody status to these diseases from laboratory testing. Blood tests for immunities to these diseases are ordinarily included in the pre-employment physical exam except for those employees who provide results of blood tests or immunization documentation from their own health care providers. Any vaccinations required for these diseases will be given at no cost in our Occupational Health office.
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