Located in Nashville, Tennessee, andoperating at a global crossroads of teaching, discovery and patientcare, VUMC is a community of individuals who come to work each daywith the simple aim of changing the world. It is a place where your expertisewill be valued, your knowledge expanded and your abilities challenged. It is aplace where your diversity â of culture, thinking, learning and leading â issought and celebrated. It is a place where employees know they are part ofsomething that is bigger than themselves, take exceptional pride in their workand never settle for what was good enough yesterday. Vanderbiltâs missionis to advance health and wellness through preeminent programs in patient care,education, and research.
At the Vanderbilt Eye Institute, we strive to make life better for adults and children with eye conditions including glaucoma, vision loss and diseases of the retina. We treat patients from across Tennessee and the Southeast. Our doctors, researchers and support staff use the latest technologies and methods, and we conduct vital vision research that translates to better treatments.
Varied Shift ; Weekend or after-hours work may be required, as needed
Inflammation and new vessel growth in the retina canlead to vision loss from swelling, bleeding, scarring, and tissue traction asseen in diabetic retinopathy and retinopathy of prematurity. Our goal is to repurpose drugs previouslydeveloped to target inflammation and vascular growth in non-ocular systems toprevent, abort, or revert these potentially blinding conditions. We use humanretinal cells from donor eyes as well as animal models to achieve thesegoals. Pharmacologic and geneticapproaches are employed in our lab to block the function of target receptors(inhibitors, siRNA, or neutralizing antibodies in culture, andreceptor knockout mouse strains or pharmacologic inhibition by drugdelivery in animal models of disease) to discover and/or develop new therapies.
Weare looking forward to working with a highly motivated individual who cancollaborate with others in lab and who exhibits a high level of technicalexpertise as well as professionalism, dedication, reliability, and intellectualcuriosity.
Key Functions and Expected Performances:
Under minimal supervision, plan and conduct complex experiments, analyze data, prepare reports, and archive data.
Plan and coordinate experiments in conjunction with Principal Investigator (PI).
b.Processand analyze data demonstrating keen analytical and problem-solving skills.
Understand and follow experimental protocols and competently perform any required assays (may include animal handling, tissue culture, etc.)
Accurately record/document, compile, organize, and communicate data/results.
Follow University safety protocols (may include use of toxic and hazardous materials, and/or carcinogens).
Perform calculations involving molarity, % solutions, and serial dilutions.
g.Performdata analysis and create graphs/reports.
Operate and maintain equipment, and, troubleshoot equipment malfunctions throughout the execution of all research projects associated with the lab.
Recommend equipment and supplies needed for research projects.
Familiarize with equipment operations and manuals.
Set up, maintain, troubleshoot and arrange to repair equipment according to manufacturer and Vanderbilt University guidelines.
Ensure laboratory is prepared for experiments.
a.Procure,organize and prepare lab supplies needed to complete the work.
Maintain sterile conditions as required.
Assist PI in modifying procedures and techniques.
Recognize problems and suggest solutions, assist in modifications.
Recommend improvements to established techniques and/or protocols (troubleshooting).
Maintain personal knowledge of scientific trends through literature reviews.
Provide appropriate written/oral documentation of experiments.
a.Effectively communicate inoral and written formats.
Prepare research progress reports.
Analyze, interpret, and summarize test results.
Assist in the effective operation of the laboratory.
Train other employees.
Supervise projects and/or personnel.
Serve as a liaison to other Vanderbilt Medical School Departments, Divisions and core facilities such as: Division of Animal Care (DAC), Institutional Animal Care and Use Committee (IACUC), Vanderbilt Environmental Health and Safety (VEHS) etc, to ensure compliance of laboratory practices and procedures with University, local and federal rules and regulations.
Preferred Education, Skills, and Experiences:
Â·Experiencein an academic research lab.
Â·2-3 years of rigorous laboratory experience or the equivalent
Â·Preferencewill be given to candidates with a demonstrated ability to communicate researchfindings through publication in high impact, peer-reviewed journals andpresentations at national meetings.
Â·Preferencewill be given to individuals who want to establish themselves in a stable longemployment relationship with the laboratory and who are interested in continuedprofessional development.
Â·Laboratoryskills that are sought include:
-Breedingmice and working with animal models of human disease.
Â·Mouse models of retinal disease (STZ-induced diabetes,ischemia-reperfusion injury, oxygen-induced retinopathy)
Â·Retinal dissection and ex-vivo analysis after therapy (leukostasisassays, vascular leakage assay (Evans blue extravasation))
Becausewe are committed to providing the best in patient care, education and research,we are proud of our recent accomplishments:
Â·US News & World Report:#1 Hospital inTennessee, #1 Health Care Provider in Nashville, #1 Audiology (Bill Wilkerson Center),12 adult and 10 pediatric clinical specialties ranked among the nation's best,#15 Education and Training
Â·Truven Health Analytics:among the top 50cardiovascular hospitals in the U.S.
Â·Becker's Hospital Review:one of the "100Greatest Hospitals in America"
Â·The Leapfrog Group:grade "A" inHospital Safety Score
Â·National Institutes of Health:among the top 10 grantawardees for medical research in the US
Â·Magnet Recognition Program:Vanderbilt nurses arethe only group honored in Tennessee
Â·Nashville Business Journal:Middle Tennessee'shealthiest employer
Â·American Hospital Association:among the 100"Most Wired" medical systems in the US
Vanderbilt University Medical Center is a comprehensive health care facility dedicated to patient care, research, and biomedical education. Our reputation for excellence in these areas has made us a major center for patient referrals from throughout the Mid-South. Each year, people throughout Tennessee and the Southeast choose Vanderbilt University Medical Center for their health care because of our leadership in medical science and our dedication to treating patients with dignity and compassion.The mission of Vanderbilt University Medical Center is to advance health and wellness through preeminent programs in patient care, education, and research.